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About this entry
Upper respiratory tract infection occurs commonly in both children and adults and is a major cause of mild morbidity. URTIs have a high cost to society, being responsible for missed work and unnecessary medical care. Most of the infections are viral in nature and some bacterial like Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. Differentiating between bacterial and viral infection is crucial before prescribing antibiotics. Even if the infection is bacterial, the spectrum of antibiotic must be considered. Our current project focuses on quantitative detection of endotoxin by lateral immunoassay using paper shunt technology. This device can also be used to demonstrate the effectiveness of antibiotics prescribed to children on subsequent clinical visits as mobile devices can measure the amount of endotoxin secreted in sputum and endotrachial secreted.