3I Diagnostics

About this entry

3I is a privately held company based in Germantown, Maryland that was formed to develop a novel diagnostic platform capable of identifying a broad range of bacteria directly from the patient sample in less than an hour. The platform is being developed in collaboration with personnel from the University of Maryland, NIST, and physicians from several leading hospitals. The team’s technical expertise includes microfluidics, spectroscopy, bacterial pathogenesis and practicing physicians. They are all based in the US and are led by Dr Rajesh Krishnamurthy.

Our solution isolates and concentrates intact microbes directly from whole blood and other sample types by (i) selectively breaking down non-microbial components, using a novel proprietary mechanical lysis technique, to a size smaller than intact microbe (ii) separating the lysis debris from intact microbe, (iii) concentrating it, (iv) acquiring the infrared spectral profile, and (v) comparing the unique signature against other signatures in a database. The solution does not involve any custom reagents (antibodies or DNA), is non-destructive, and can capture and identify a broad range of pathogens in 15-60 minutes.

If you would like to be introduced to this team for collaboration, get in touch with the Longitude prize.
Pathogen(s)
Respiratory Tract Infection Tuberculosis Sepsis (we are focusing on blood & sputum initially, but intend to cover all clinical matrices)